Chest ACCP Career Connection
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Guest Access | Sign In via User Name/Password
This Article
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Article Archive
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Baydur, A
Right arrow Articles by Fischer, D.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Baydur, A
Right arrow Articles by Fischer, D.

Chest, Vol 97, 884-889, Copyright © 1990 by American College of Chest Physicians

ARTICLES

Decline in respiratory function and experience with long-term assisted ventilation in advanced Duchenne's muscular dystrophy

A Baydur, I Gilgoff, W Prentice, M Carlson and DA Fischer
Chest Medicine and Pediatrics Services, Rancho Los Amigos Medical Center, Downey, CA.

We present 17 patients with advanced DMD who required long-term assisted ventilation. Eleven patients used part-time assisted ventilation. Five of the patients received BV and/or M-IPPV or N-IPPV between two and nine years before requiring full-time T-IPPV, while six others initially used part-time T-IPPV. One patient used all three modes before requiring full-time T-IPPV. Mean (+/- SD) FVC and rebreathe PCO2 at the outset of assisted ventilation were 0.62 +/- 0.20 L and 47.4 +/- 7.5 mm Hg, respectively. Clinical features were divided between symptoms suggesting respiratory muscle fatigue and sleep- related disordered breathing. We found that, while useful in early respiratory insufficiency, BV is associated with recurrent aspiration. In our experience, N-IPPV offers the safest and most convenient form of noninvasive ventilation. When the VC has decreased to about 300 ml, most patients will require full-time ventilation; T-IPPV is advised to provide airway access to suction secretions.


This article has been cited by other articles:


Home page
 Eur Respir JHome page
M. Toussaint, M. Steens, G. Wasteels, and P. Soudon
Diurnal ventilation via mouthpiece: survival in end-stage Duchenne patients
Eur. Respir. J., September 1, 2006; 28(3): 549 - 555.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
Respiratory Care of the Patient with Duchenne Muscular Dystrophy: ATS Consensus Statement
Am. J. Respir. Crit. Care Med., August 15, 2004; 170(4): 456 - 465.
[Full Text] [PDF]

Home page
 ThoraxHome page
J D ROAD
Assisted ventilation for chronic neuromuscular disorders
Thorax, January 1, 2000; 55(1): 1 - 2.
[Full Text]

Home page
 ThoraxHome page
A. Baydur, E. Layne, H. Aral, N. Krishnareddy, R. Topacio, G. Frederick, and W. Bodden
Long term non-invasive ventilation in the community for patients with musculoskeletal disorders: 46 year experience and review
Thorax, January 1, 2000; 55(1): 4 - 11.
[Abstract] [Full Text]

Home page
 Am. J. Respir. Crit. Care Med.Home page
M. F. PHILLIPS, P. E. M. SMITH, N. CARROLL, R. H. T. EDWARDS, and P. M. A. CALVERLEY
Nocturnal Oxygenation and Prognosis in Duchenne Muscular Dystrophy
Am. J. Respir. Crit. Care Med., July 1, 1999; 160(1): 198 - 202.
[Abstract] [Full Text]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
M. I Polkey, R. A Lyall, J. Moxham, and P N. Leigh
Respiratory aspects of neurological disease
J. Neurol. Neurosurg. Psychiatry, January 1, 1999; 66(1): 5 - 15.
[Full Text]

Home page
 ThoraxHome page
A K Simonds, F Muntoni, S Heather, and S Fielding
Impact of nasal ventilation on survival in hypercapnic Duchenne muscular dystrophy
Thorax, November 1, 1998; 53(11): 949 - 952.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1990 by the American College of Chest Physicians.