| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
Guest Access | Sign In via User Name/Password
|
|
|
|||||||
Guest Access | Sign In via User Name/Password |
|||||||||
Chest, Vol 98, 693-698, Copyright © 1990 by American College of Chest Physicians
ARTICLES |
EH Gluck, DJ Onorato and R Castriotta
Hartford Hospital, CT.
Seven patients with status asthmaticus intubated for respiratory failure who had elevated airway pressures and persistent respiratory acidosis were successfully ventilated using a mixture of 60 percent helium and 40 percent oxygen. All patients experienced a rapid reduction in airway pressures, CO2 retention, and resolution of acidosis while breathing a helium-oxygen mixture. There were no untoward effects. Helium-oxygen mixtures improve ventilation by reducing the Reynolds number and reducing density dependent resistance. Helium's beneficial effects are due to its high kinematic viscosity, high binary diffusion coefficient for CO2, and high diffusivity. Helium- oxygen mixtures should be considered for use in mechanically ventilated asthmatics with respiratory acidosis who fail conventional therapy.
This article has been cited by other articles:
|
|
 |
|
  S. Dhuper, S. Choksi, S. Selvaraj, G. Jha, A. Ahmed, H. Babbar, B. Walia, A. Chandra, V. Chung, and C. Shim Room Air Entrainment During {beta}-Agonist Delivery With Heliox. Chest, October 1, 2006; 130(4): 1063 - 1071. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. M. Schreck Asthma pathophysiology and evidence-based treatment of severe exacerbations. Am. J. Health Syst. Pharm., May 15, 2006; 63(10 Suppl 3): S5 - 13. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. R. McFadden Jr. Acute Severe Asthma Am. J. Respir. Crit. Care Med., October 1, 2003; 168(7): 740 - 759. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. E. Kass Heliox Redux Chest, March 1, 2003; 123(3): 673 - 676. [Full Text] [PDF]
|
|
|
|
|
|
A. M.-H. Ho, A. Lee, M. K. Karmakar, P. W. Dion, D. C. Chung, and L. H. Contardi Heliox vs Air-Oxygen Mixtures for the Treatment of Patients With Acute Asthma: A Systematic Overview Chest, March 1, 2003; 123(3): 882 - 890. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P Phipps and C S Garrard The pulmonary physician in critical care * 12: Acute severe asthma in the intensive care unit Thorax, January 1, 2003; 58(1): 81 - 88. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. P. Kress, I. Noth, B. K. Gehlbach, N. Barman, A. S. Pohlman, A. Miller, S. Morgan, and J. B. Hall The Utility of Albuterol Nebulized with Heliox during Acute Asthma Exacerbations Am. J. Respir. Crit. Care Med., May 1, 2002; 165(9): 1317 - 1321. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Oppenheim-Eden, Y. Cohen, C. Weissman, and R. Pizov The Effect of Helium on Ventilator Performance : Study of Five Ventilators and a Bedside Pitot Tube Spirometer Chest, August 1, 2001; 120(2): 582 - 588. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. KATZ, M. A. GENTILE, D. M. CRAIG, G. QUICK, J. N. MELIONES, and I. M. CHEIFETZ Heliox Improves Gas Exchange during High-frequency Ventilation in a Pediatric Model of Acute Lung Injury Am. J. Respir. Crit. Care Med., July 15, 2001; 164(2): 260 - 264. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. A. Werner Status Asthmaticus in Children : A Review Chest, June 1, 2001; 119(6): 1913 - 1929. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. L. GOODE, J. B. FINK, R. DHAND, and M. J. TOBIN Improvement in Aerosol Delivery with Helium-Oxygen Mixtures during Mechanical Ventilation Am. J. Respir. Crit. Care Med., January 1, 2001; 163(1): 109 - 114. [Abstract] [Full Text]
|
|
|
|
 |
|
 D. O. Kuethe, A. Caprihan, H. M. Gach, I. J. Lowe, and E. Fukushima Imaging obstructed ventilation with NMR using inert fluorinated gases J Appl Physiol, June 1, 2000; 88(6): 2279 - 2286. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. JABER, R. FODIL, A. CARLUCCI, M. BOUSSARSAR, J. PIGEOT, F. LEMAIRE, A. HARF, F. LOFASO, D. ISABEY, and L. BROCHARD Noninvasive Ventilation with Helium-Oxygen in Acute Exacerbations of Chronic Obstructive Pulmonary Disease Am. J. Respir. Crit. Care Med., April 1, 2000; 161(4): 1191 - 1200. [Abstract] [Full Text]
|
|
|
|
|
|
J. E. Kass and C. A. Terregino The Effect of Heliox in Acute Severe Asthma: A Randomized Controlled Trial Chest, August 1, 1999; 116(2): 296 - 300. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. A. Jantz and N. A. Collop Bronchodilator Aerosol Delivery in Mechanical Ventilation: Jantz MA, Collop NA Bronchodilator Aerosol Delivery in Mechanical Ventilation Intensive Care Med 1999,14 166-183 J Intensive Care Med, July 1, 1999; 14(4): 166 - 183. [PDF]
|
|
|
|
|
|
D. TASSAUX, P. JOLLIET, J.-M. THOURET, J. ROESELER, R. DORNE, and J.-C. CHEVROLET Calibration of Seven ICU Ventilators for Mechanical Ventilation with Helium-Oxygen Mixtures Am. J. Respir. Crit. Care Med., July 1, 1999; 160(1): 22 - 32. [Abstract] [Full Text]
|
|
|
|
|
|
J. G. Michael, T. Bocklage, and J. D. Tobias Helium Administration During Mechanical Ventilation in Children with Respiratory Failure: Michael JG, Bocklage T, Tobias JD Helium administration during mechanical ventilation in children with respiratory failure J Intensive Care Med 1999,14 140-147 J Intensive Care Med, May 1, 1999; 14(3): 140 - 147. [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
