Chest ACCP Member Benefits
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Guest Access | Sign In via User Name/Password
This Article
Right arrow Full Text (PDF) Free
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Article Archive
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Scott, G.
Right arrow Articles by Burki, N.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Scott, G.
Right arrow Articles by Burki, N.

Chest, Vol 98, 900-906, Copyright © 1990 by American College of Chest Physicians

ARTICLES

The relationship of resting ventilation to mouth occlusion pressure. An index of resting respiratory function

GC Scott and NK Burki
Department of Medicine, University of Kentucky, Lexington.

In order to examine the relationship of mouth occlusion pressure (MOP), an index of central inspiratory neuromuscular drive, to age and sex and to resting ventilation (VE), measurements were made in the seated posture in 84 healthy, normal subjects (38 men, 46 women; ages 18-72 years, mean +/- SD = 39.8 +/- 14.5 years) and in 79 patients with either airways obstruction (n = 63) or restrictive lung disease (n = 16). In the normal subjects, there was no significant relationship between age or sex and MOP (expressed as P0.1), which is the mouth pressure developed against a complete occlusion at 0.1 s after the beginning of inspiration, and dP/dtmax, the maximal rate of rise of this pressure; mean +/- SD for P0.1 = 0.75 +/- 0.32 cmH2O, and dP/dtmax = 19.41 +/- 10.10 cmH2O/s. Similarly, there was no significant relationship between age or sex and VE/P0.1 or VE/dP/dtmax. In 99 percent of normal subjects (83 of 84), VE/P0.1 was greater than 8.0 L/min/cmH2O, whereas in only 1 of the 79 patients was the value greater than 7.9 L/min/cmH2O. While the mean values of P0.1 and dP/dtmax were significantly different between normal subjects and patients, there was considerable overlap, whereas the ratio VE/P0.1 or VE/dP/dtmax provided excellent differentiation between normal subjects and patients with lung disease. This index, which is easily measured and requires minimal patient cooperation, provides valuable information in the clinical assessment of ventilatory drive and lung mechanics.


This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
C. H. Huang, A. D. Martin, and P. W. Davenport
Effect of inspiratory muscle strength training on inspiratory motor drive and RREP early peak components
J Appl Physiol, February 1, 2003; 94(2): 462 - 468.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
O. Hafstrom, J. Milerad, and H. W. Sundell
Altered Breathing Pattern after Prenatal Nicotine Exposure in the Young Lamb
Am. J. Respir. Crit. Care Med., July 1, 2002; 166(1): 92 - 97.
[Abstract] [Full Text] [PDF]

Home page
 PediatricsHome page
D. A. Fitzgerald, G. Mesiano, L. Brosseau, and G. M. Davis
Pulmonary Outcome in Extremely Low Birth Weight Infants
Pediatrics, June 1, 2000; 105(6): 1209 - 1215.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1990 by the American College of Chest Physicians.