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Chest, Vol 99, 1529-1530, Copyright © 1991 by American College of Chest Physicians

ARTICLES

Elevated serum levels of tumor necrosis factor-alpha after bronchoscopy and bronchoalveolar lavage

TJ Standiford, SL Kunkel and RM Strieter
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor 48109-0360.

Fiberoptic bronchoscopy and bronchoalveolar lavage are often followed by the development of fever and other influenza-like symptoms. We report the onset of these symptoms in a healthy volunteer following bronchoscopy and bronchoalveolar lavage; the symptoms were temporally associated with the dramatic elevation of serum levels of tumor necrosis factor. Our observations suggest that tumor necrosis factor may be involved in mediating fever and other influenza-like symptoms occurring after bronchoscopy.


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Copyright © 1991 by the American College of Chest Physicians.