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clinical investigations in critical care: Steven Osmon, David Warren, Sondra M. Seiler, William Shannon, Victoria J. Fraser, and Marin H. Kollef The Influence of Infection on Hospital Mortality for Patients Requiring > 48 h of Intensive Care Chest 2003; 124: 1021-1029 [Abstract] [Full text] [PDF]

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Chronic obstructive pulmonary disease and nosocomial infections

Prashant S Borade, Daniel K C Lee, MB, BCh, MRCP, MD   (17 February 2005)

Chronic obstructive pulmonary disease and nosocomial infections 17 February 2005
Prashant S Borade, MB, BS, MD Department of Respiratory Medicine, Ipswich Hospital, Ipswich, Suffolk, England, United Kingdom, Daniel K C Lee, MB, BCh, MRCP, MD Send letter to journal: Re: Chronic obstructive pulmonary disease and nosocomial infections psborade{at}hotmail.com Prashant S Borade, et al.	Chronic obstructive pulmonary disease (COPD) predisposes an individual to community-acquired infections. However, the relationship between COPD and nosocomial infections is less clear. A prospective study was conducted in 499 consecutive patients admitted to the intensive care unit without clinical or laboratory evidence of community-acquired infections over a 6-month period. The incidence of nosocomial infections was not significantly different comparing patients with COPD (26%) and without COPD (20%). Mortality was 47% in ventilated patients. Patients with COPD are no more susceptible to develop nosocomial infections than patients without COPD.