editorials

"Vital" Sign?

Stephen Trzeciak and Michael E. Chansky
Chest 130: 933-934 [Full Text] [PDF]  

Pulmonary Hypertension Trials: Current End Points Are Flawed, But What Are the Alternatives?

Kari Roberts, Ioana Preston, and Nicholas S. Hill
Chest 130: 934-936 [Full Text] [PDF]  

Lung Cancer: Family History Matters

Ann G. Schwartz
Chest 130: 936-937 [Full Text] [PDF]  

Did Lady Windermere Have Cystic Fibrosis?

Bruce K. Rubin
Chest 130: 937-938 [Full Text] [PDF]  

Optimal Therapy for Methicillin-Resistant Staphylococcus aureus Pneumonia: What Is the Best Dosing Regimen?

Jordi Rello and Jordi Mallol
Chest 130: 938-940 [Full Text] [PDF]  

original research CRITICAL CARE MEDICINE

Emergency Department Hypotension Predicts Sudden Unexpected In-hospital Mortality: A Prospective Cohort Study

Alan E. Jones, Vasilios Yiannibas, Charles Johnson, and Jeffrey A. Kline
Chest 130: 941-946 [Abstract] [Full Text] [PDF]  

Predictors of Mortality for Methicillin-Resistant Staphylococcus aureus Health-Care–Associated Pneumonia: Specific Evaluation of Vancomycin Pharmacokinetic Indices

Meghan N. Jeffres, Warren Isakow, Joshua A. Doherty, Peggy S. McKinnon, David J. Ritchie, Scott T. Micek, and Marin H. Kollef
Chest 130: 947-955 [Abstract] [Full Text] [PDF]  

Agreement Between Quantitative Cultures of Postintubation Tracheal Aspiration and Plugged Telescoping Catheter, Protected Specimen Brush, or BAL for the Diagnosis of Nosocomial Pneumonia

Christophe Clec’h, Françoise Jauréguy, Lilia Hamza, Philippe Karoubi, Jean-Philippe Fosse, Aïcha Hamdi, François Vincent, Frédéric Gonzalez, and Yves Cohen
Chest 130: 956-961 [Abstract] [Full Text] [PDF]  

Hyperchloremic Acidosis Increases Circulating Inflammatory Molecules in Experimental Sepsis

John A. Kellum, Mingchen Song, and Eyad Almasri
Chest 130: 962-967 [Abstract] [Full Text] [PDF]  

original research LUNG CANCER

Association Between Lung Cancer Incidence and Family History of Lung Cancer: Data From a Large-Scale Population-Based Cohort Study, the JPHC Study

Jun-ichi Nitadori, Manami Inoue, Motoki Iwasaki, Tetsuya Otani, Shizuka Sasazuki, Kanji Nagai, Shoichiro Tsugane the JPHC Study Group
Chest 130: 968-975 [Abstract] [Full Text] [PDF]  

original research INTERSTITIAL LUNG DISEASE

Unique Characteristics of Systemic Sclerosis Sine Scleroderma-Associated Interstitial Lung Disease

Aryeh Fischer, Richard T. Meehan, Carol A. Feghali-Bostwick, Sterling G. West, and Kevin K. Brown
Chest 130: 976-981 [Abstract] [Full Text] [PDF]  

Different Angiogenic Activity in Pulmonary Sarcoidosis and Idiopathic Pulmonary Fibrosis

Katerina M. Antoniou, Argyris Tzouvelekis, Michael G. Alexandrakis, Katerina Sfiridaki, Ioanna Tsiligianni, George Rachiotis, Nikolaos Tzanakis, Demosthenes Bouros, Joseph Milic-Emili, and Nikolaos M. Siafakas
Chest 130: 982-988 [Abstract] [Full Text] [PDF]  

Fatigue Is Associated With Quality of Life in Sarcoidosis Patients

Helen J. Michielsen, Marjolein Drent, Tatjana Peros-Golubicic, and Jolanda De Vries
Chest 130: 989-994 [Abstract] [Full Text] [PDF]  

original research CYSTIC FIBROSIS

Prospective Analysis of Cystic Fibrosis Transmembrane Regulator Mutations in Adults With Bronchiectasis or Pulmonary Nontuberculous Mycobacterial Infection

Tomasz M. Ziedalski, Peter N. Kao, Noreen R. Henig, Susan S. Jacobs, and Stephen J. Ruoss
Chest 130: 995-1002 [Abstract] [Full Text] [PDF]  

original research SLEEP MEDICINE

The Effect of 1 Week of Continuous Positive Airway Pressure Treatment in Obstructive Sleep Apnea Patients With Concomitant Gastroesophageal Reflux

Maroun Tawk, Suanne Goodrich, Gary Kinasewitz, and William Orr
Chest 130: 1003-1008 [Abstract] [Full Text] [PDF]  

Twenty-Four–Hour Ambulatory BP in Snoring Children With Obstructive Sleep Apnea Syndrome

Lettie C.K. Leung, Daniel K. Ng, Michael W. Lau, Chung-hong Chan, Ka-li Kwok, Pok-yu Chow, and Josephine M.Y. Cheung
Chest 130: 1009-1017 [Abstract] [Full Text] [PDF]  

Pressure-Relief Continuous Positive Airway Pressure vs Constant Continuous Positive Airway Pressure: A Comparison of Efficacy and Compliance

Georg Nilius, Andreas Happel, Ulrike Domanski, and Karl-Heinz Ruhle
Chest 130: 1018-1024 [Abstract] [Full Text] [PDF]  

original research ASTHMA

Abnormalities of the Bronchial Arteries in Asthma

Francis H. Y. Green, John C. Butt, Alan L. James, and Neil G. Carroll
Chest 130: 1025-1033 [Abstract] [Full Text] [PDF]  

Depressive Symptoms and Adherence to Asthma Therapy After Hospital Discharge

Amena Smith, Jerry A. Krishnan, Andrew Bilderback, Kristin A. Riekert, Cynthia S. Rand, and Susan J. Bartlett
Chest 130: 1034-1038 [Abstract] [Full Text] [PDF]  

What Is Worse for Asthma Control and Quality of Life: Depressive Disorders, Anxiety Disorders, or Both?

Kim L. Lavoie, Simon L. Bacon, Silvana Barone, Andre Cartier, Blaine Ditto, and Manon Labrecque
Chest 130: 1039-1047 [Abstract] [Full Text] [PDF]  

Increase in Concentration of Soluble CD86 After Segmental Allergen Challenge in Patients With Allergic Asthma

Xiang-Dong Liang, Huan-Zhong Shi, Xue-Jun Qin, and Jing-Min Deng
Chest 130: 1048-1054 [Abstract] [Full Text] [PDF]  

Evaluation of Asthma With Hyperpolarized Helium-3 MRI: Correlation With Clinical Severity and Spirometry

Eduard E. de Lange, Talissa A. Altes, James T. Patrie, John D. Gaare, Jeffrey J. Knake, John P. Mugler, III, and Thomas A. Platts-Mills
Chest 130: 1055-1062 [Abstract] [Full Text] [PDF]  

Room Air Entrainment During ß-Agonist Delivery With Heliox

Sunil Dhuper, Sonia Choksi, Simdararajan Selvaraj, Gautam Jha, Aziz Ahmed, Harsh Babbar, Baljit Walia, Alpana Chandra, Virginia Chung, and Chang Shim
Chest 130: 1063-1071 [Abstract] [Full Text] [PDF]  

Dynamic Hyperinflation During Bronchoconstriction in Asthma: Implications for Symptom Perception

M. Diane Lougheed, Thomas Fisher, and Denis E. O’Donnell
Chest 130: 1072-1081 [Abstract] [Full Text] [PDF]  

original research COPD

Use of Inhaled Corticosteroids and the Risk of Fracture

Richard Hubbard, Anne Tattersfield, Chris Smith, Joe West, Liam Smeeth, and Astrid Fletcher
Chest 130: 1082-1088 [Abstract] [Full Text] [PDF]  

Effect of Rollator Use on Health-Related Quality of Life in Individuals With COPD

Renu B. Gupta, Dina Brooks, Yves Lacasse, and Roger S. Goldstein
Chest 130: 1089-1095 [Abstract] [Full Text] [PDF]  

Role of Gastroesophageal Reflux Symptoms in Exacerbations of COPD

Ivan E. Rascon-Aguilar, Mark Pamer, Peter Wludyka, James Cury, David Coultas, Louis R. Lambiase, N. Stanley Nahman, and Kenneth J. Vega
Chest 130: 1096-1101 [Abstract] [Full Text] [PDF]  

Epithelial Mucin Stores Are Increased in the Large Airways of Smokers With Airflow Obstruction

Anh L. Innes, Prescott G. Woodruff, Ronald E. Ferrando, Samantha Donnelly, Gregory M. Dolganov, Stephen C. Lazarus, and John V. Fahy
Chest 130: 1102-1108 [Abstract] [Full Text] [PDF] [Online supplemental file]  

Impact of a Winter Respiratory Virus Season on Patients With COPD and Association With Influenza Vaccination

Geoffrey J. Gorse, Theresa Z. O’Connor, Stephen L. Young, Michael P. Habib, Janet Wittes, Kathleen M. Neuzil, and Kristin L. Nichol
Chest 130: 1109-1116 [Abstract] [Full Text] [PDF]  

Does Quality of Life of COPD Patients as Measured by the Generic EuroQol Five-Dimension Questionnaire Differentiate Between COPD Severity Stages?

Maureen P.M.H. Rutten-van Mölken, Jan B. Oostenbrink, Donald P. Tashkin, Deborah Burkhart, and Brigitta U. Monz
Chest 130: 1117-1128 [Abstract] [Full Text] [PDF]  

Thirty-Year Cumulative Incidence of Chronic Bronchitis and COPD in Relation to 30-Year Pulmonary Function and 40-Year Mortality: A Follow-up in Middle-Aged Rural Men

Margit Pelkonen, Irma-Leena Notkola, Aulikki Nissinen, Hannu Tukiainen, and Heikki Koskela
Chest 130: 1129-1137 [Abstract] [Full Text] [PDF]  

original research SURGERY

Chylothorax Complicating Repairs of the Descending and Thoracoabdominal Aorta

Adnan H. Allaham, Anthony L. Estrera, Charles C. Miller, III, Paul Achouh, and Hazim J. Safi
Chest 130: 1138-1142 [Abstract] [Full Text] [PDF]  

Nontraumatic Disruption of the Fibrocartilaginous Trachea: Causes and Clinical Outcomes

Michelle R. Aerni, Joseph G. Parambil, Mark S. Allen, and James P. Utz
Chest 130: 1143-1149 [Abstract] [Full Text] [PDF]  

Air Leaks After Lobectomy Increase the Risk of Empyema but Not of Cardiopulmonary Complications: A Case-Matched Analysis

Alessandro Brunelli, Francesco Xiume, Majed Al Refai, Michele Salati, Rita Marasco, and Armando Sabbatini
Chest 130: 1150-1156 [Abstract] [Full Text] [PDF]  

original research SPUTUM INDUCTION

Repeated Sputum Inductions Induce a Transient Neutrophilic and Eosinophilic Response

Hester van der Vaart, Dirkje S. Postma, Wim Timens, Henk F. Kauffman, Machteld N. Hylkema, and Nick H.T. ten Hacken
Chest 130: 1157-1164 [Abstract] [Full Text] [PDF]  

original research COMMUNITY ACQUIRED PNEUMONIA

Long-term Symptom Recovery and Health-Related Quality of Life in Patients With Mild-to-Moderate-Severe Community-Acquired Pneumonia

Rachida el Moussaoui, Brent C. Opmeer, Corianne A.J.M. de Borgie, Pythia Nieuwkerk, Patrick M.M. Bossuyt, Peter Speelman, and Jan M. Prins
Chest 130: 1165-1172 [Abstract] [Full Text] [PDF]  

original research INTERVENTIONAL PULMONOLOGY

Pathophysiology of Pneumothorax Following Ultrasound-Guided Thoracentesis

Jay Heidecker, John T. Huggins, Steven A. Sahn, and Peter Doelken
Chest 130: 1173-1184 [Abstract] [Full Text] [PDF]  

The Safety of Bronchoscopy in a Pulmonary Fellowship Program

Daniel R. Ouellette
Chest 130: 1185-1190 [Abstract] [Full Text] [PDF]  

Differentiating Peripheral Pulmonary Lesions Based on Images of Endobronchial Ultrasonography

Tung-Ying Chao, Chien-Hao Lie, Yu-Hsiu Chung, Jui-Long Wang, Yi-Hsi Wang, and Meng-Chih Lin
Chest 130: 1191-1197 [Abstract] [Full Text] [PDF]  

clinical commentary PULMONARY HYPERTENSION

The Current Treatment of Pulmonary Arterial Hypertension: Time to Redefine Success

Stuart Rich
Chest 130: 1198-1202 [Abstract] [Full Text] [PDF]  

translating basic research into clinical practice

How Viral Infections Cause Exacerbation of Airway Diseases

Patrick Mallia and Sebastian L. Johnston
Chest 130: 1203-1210 [Abstract] [Full Text] [PDF]  

recent advances in chest medicine

Advances in Chemotherapy of Non-small Cell Lung Cancer

Julian R. Molina, Alex A. Adjei, and James R. Jett
Chest 130: 1211-1219 [Abstract] [Full Text] [PDF]  

special features

Diagnostic Usefulness of B-Type Natriuretic Peptide and Functional Consequences of Muscle Alterations in COPD and Chronic Heart Failure

Sanja Jelic and Thierry H. Le Jemtel
Chest 130: 1220-1230 [Abstract] [Full Text] [PDF]  

topics in practice management

Smoking Cessation Counseling: A Practice Management Perspective

Carol Pohlig
Chest 130: 1231-1233 [Abstract] [Full Text] [PDF]  

selected reports

The Expanding Spectrum of Mycobacterium avium Complex-Associated Pulmonary Disease

E. Andrew Waller, Archana Roy, Lisa Brumble, Andras Khoor, Margaret M. Johnson, and Jeffrey L. Garland
Chest 130: 1234-1241 [Abstract] [Full Text] [PDF]  

A 37-Year-Old Woman With Multiple Pulmonary Nodular Opacities and Hemoptysis

Sebastián Gando, Fernando Villarejo, Bernardo Maskin, and Carlos M. Luna
Chest 130: 1241-1243 [Full Text] [PDF]  

postgraduate education corner PULMONARY AND CRITICAL CARE PEARLS

Recurrent Dyspnea on Exertion in a 71-Year-Old Man With Prior Pulmonary Embolism

Anil Singh, Christian LaFalce, Gary Marrone, Daniel Shade, and Navdeep Singh
Chest 130: 1244-1247 [Full Text] [PDF]  

A 48-Year-Old Woman With Multiple Pulmonary Nodules and a Right Ventricular Mass

Kelsey Gray, Edward D. Chan, and Julia Alvarado
Chest 130: 1248-1251 [Full Text] [PDF]  

postgraduate education corner CONTEMPORARY REVIEWS IN SLEEP MEDICINE

A Review of Pediatric Nonrespiratory Sleep Disorders

Melisa Moore, David Allison, and Carol L. Rosen
Chest 130: 1252-1262 [Abstract] [Full Text] [PDF]  

postgraduate education corner MEDICAL WRITING TIPS

Documenting Research in Scientific Articles: Guidelines for Authors: Reporting Research Designs and Activities

Tom Lang
Chest 130: 1263-1268 [Full Text] [PDF]  

postgraduate education corner CASE RECORDS OF THE UNIVERSITY OF COLORADO

A 70-Year-Old Man With Migratory Pulmonary Infiltrates

Adam L. Friedlander and Michael B. Fessler
Chest 130: 1269-1274 [Full Text] [PDF]  

correspondence

Is the More (Intricate) the Better?

Stefan Kostianev, Blagoi Marinov, Dimitar Iluchev, Domenico Toraldo, Giuseppe Nicolardi, Francesco De Nuccio, and Nicolino Ambrosino
Chest 130: 1275-1276 [Full Text] [PDF]  

d-ROMs Test Detects Ceruloplasmin, Not Oxidative Stress

Mehmet Ibrahim Harma, Muge Harma, Ozcan Erel, Konstantinos Kostikas, Evangelia Papageorgiou, Theodoros S. Kiropoulos, and Konstantinos I. Gourgoulianis
Chest 130: 1276-1277 [Full Text] [PDF]  

Is Endobronchial Ultrasound Necessary for Transbronchial Lung Biopsy in Solitary Pulmonary Nodule?

Ko-Pen Wang, Armin Ernst, Felix Herth, Ralph Eberhard, and Heinrich Becker
Chest 130: 1277-1278 [Full Text] [PDF]  

Is Intensive Insulin Therapy Safe in the Critically Ill?

Mohamed Y. Rady, Shahir S. Hamdulay, Hugh Montgomery, Ali Al-Khafaji, Julie M. Marchant, Anne B. Chang, and Bruce K. Rubin
Chest 130: 1278-1281 [Full Text] [PDF]  

Evaluation of the Causes of Racial Disparity in Surgical Treatment of Early-Stage Lung Cancer

Daniel S. Dube and Bruno DiGiovine
Chest 130: 1281-1282 [Full Text] [PDF]  

Severe Sepsis Due to Melioidosis

Bart L. De Keulenaer and Allen C. Cheng
Chest 130: 1282 [Full Text] [PDF]  

Left Ventricular Diastolic Abnormalities in Obese Subjects

Miguel A. Arias, Alberto Alonso-Fernández, and Francisco García-Río
Chest 130: 1282-1283 [Full Text] [PDF]  

Respiratory Research Output

Martyn R. Partridge and Grant Lewison
Chest 130: 1283 [Full Text] [PDF]  

Attention to Doping Controls Required When Prescribing for Athletes

Andrew McD. Johnston
Chest 130: 1283-1284 [Full Text] [PDF]  

Is Bronchoscopy Dangerous in the Pretreatment Workup of Non-small Cell Lung Cancer Patients?

Rocco Trisolini, Daniela Paioli, and Marco Patelli
Chest 130: 1284 [Full Text] [PDF]  

Complete Response Following Preoperative Chemotherapy for Resectable Non-small Cell Lung Cancer

Maria Serra, Lucia Occhionero, and Domenico Galetta
Chest 130: 1284-1285 [Full Text] [PDF]  

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