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Contents: Volume 83/Number 5 Supplement/May, 1983 [Index by Author]
"25th Aspen Lung Conference: Lung Defense, Injury and Repair"
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Table of Contents (PDF) | Editorial Board (PDF) | Front Matter (PDF) | Back Matter (PDF)

To see an article, click its [Full Text] or [PDF] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

ARTICLES

Introduction
John E. Repine Chest May 1983: 1S. [PDF]

Lung Defense: The Paradox of Inflammation
Gary L. Larsen, Debra A. Parrish, and Peter M. Henson Chest May 1983: 1S–5S. [PDF]

Protein-Calorie Malnutrition Impairs Cell-Mediated Immunity in the Rat Lung
Thomas R. Martin, Leonard C. Altman, and Olav Alvarez Chest May 1983: 5S. [PDF]

The Smoking Gun: Mechanism of Methylprednisolone Prevention of Bleomycin-Induced Pulmonary Fibrosis
William J. Koenig, Carroll E. Cross, Thomas W. Hesterberg, and Jerold A. Last Chest May 1983: 5S–7S. [PDF]

Genetic Control of Experimental Murine Hypersensitivity Pneumonitis
Barbara D. Wilson, John L. Sternick, Yasuyuki Yoshizawa, Anna-Luise Katzenstein, and Vernon L. Moore Chest May 1983: 8S–9S. [PDF]

A Murine Model of Asbestosis
B. E. Bozelka, P. Sestini, Y. Hammad, L. Lenzini, H. R. Gaumer, and J. E. Salvaggio Chest May 1983: 9S–10S. [PDF]

Actin-Containing Microfilaments of Pulmonary Epithelial Cells Provide a Mechanism for Translocating Asbestos to the Interstitium
Arnold R. Brody, Lila H. Hill, William S. Stirewalt, and Kenneth B. Adler Chest May 1983: 11S–12S. [PDF]

Granulocytes Alter Endothelial Cell Cytoskeletons: Potential Contribution To Regulation Of Vascular Permeability
D. Michael Shasby, Sandra S. Shasby, James M. Sullivan, and Michael J. Peach Chest May 1983: 12S–13S. [PDF]

Platelet-Activating Factor Causes Neutrophil Accumulation and Edema in Rabbit Lungs
G. S. Worthen, A. J. Goins, B. C. Mitchel, G. L. Larsen, J. R. Reeves, and P. M. Henson Chest May 1983: 13S–15S. [PDF]

Legionnaires' Pneumonia in Guinea Pigs and Rats Produced by Aerosol Exposure
Gerald S. Davis, Washington C. Winn, Jr., Dieter W. Gump, John M. Craighead, and Harry N. Beaty Chest May 1983: 15S–16S. [PDF]

Leukocytes in Lung Injury
Dale E. Hammerschmidt Chest May 1983: 16S–20S. [PDF]

Neutrophil Depletion Does Not Prevent Oxygen-Induced Lung Injury in Rabbits
J. Usha Raj and Richard D. Bland Chest May 1983: 20S–21S. [PDF]

Role of Blood Components in Mediating Lung Vascular Injury after Pulmonary Vascular Thrombosis
A. B. Malik, A. Johnson, M. V. Tahamont, Hoyte van der Zee, and F. A. Blumenstock Chest May 1983: 21S–24S. [Abstract] [PDF]

Pulmonary Vasoconstriction and Profound Leukopenia in Two Sheep Experimental Models: Effects of Complement Depletion
P. C. Hüttemeier, D. Berry, K. J. Bloch, W. D. Watkins, and W. M. Zapol Chest May 1983: 24S–25S. [PDF]

Endotoxin and Oxygen Injury to Lung Endothelium
Edward R. Block Chest May 1983: 25S–26S. [PDF]

Reduction of Lung Injury by Human Surfactant Treatment in Respiratory Distress Syndrome
T. Allen Merritt, Charles G. Cochrane, Mikko Hallman, Katherine E. Holcomb, David Strayer, Frank Mannino, David K. Edwards, III, and Louis Gluck Chest May 1983: 27S–31S. [PDF]

Lung Lavage of Newborns with Respiratory Distress Syndrome: Prolonged Neutrophil Influx is Associated with Bronchopulmonary Dysplasia
Bruce E. Ogden, Shirley Murphy, George C. Saunders, and John D. Johnson Chest May 1983: 31S–33S. [PDF]

Hyperoxia Injures Endothelial Cells in Culture and Causes Increased Neutrophil Adherence
C. Michael Bowman, Elaine N. Butler, Albert E. Vatter, and John E. Repine Chest May 1983: 33S–35S. [PDF]

Pulmonary Oxygen Toxicity: Bronchoalveolar Lavage Demonstration of Early Parameters of Alveolitis
W. B. Davis, S. I. Rennard, P. B. Bitterman, J. E. Gadek, X. H. Sun, M. Wewers, B. A. Keogh, and R. G. Crystal Chest May 1983: 35S. [PDF]

Oxygen Radicals and Lung Injury: The State of the Art
Joe M. McCord Chest May 1983: 35S–37S. [PDF]

Tissue Levels of Vitamin E in the Lung and the Cellular Response to Injury Resulting from Oxidant Gas Exposure
R. J. Stephens, D. J. Buntman, D. S. Negi, R. M. Parkhurst, and D. W. Thomas Chest May 1983: 37S–39S. [PDF]

Changes in O₂ Toxicity and Glutathione Peroxidase Levels in Selenium Deficient Rats
Susan M. Deneke, Stanley N. Gershoff, and Barry L. Fanburg Chest May 1983: 39S–40S. [PDF]

Pulmonary Arterial Wall Injury and Remodelling by Hyperoxia
Rosemary Jones, W. M. Zapol, and Lynne Reid Chest May 1983: 40S–42S. [PDF]

Alveolar Injury by Oxygen Metabolites Alters the Composition of Extracellular Matrix
Robert E. Sandblom, Leonard D. Hudson, Kent J. Johnson, Paul D. Killen, Gary E. Striker, and Helene Sage Chest May 1983: 42S–43S. [PDF]

A Comparative Study of Pulmonary Fibrosis Induced by Bleomycin and an O₂ Metabolite Producing Enzyme System
Sem H. Phan, Gregg Armstrong, Mark C. Sulavik, Denis Schrier, Kent J. Johnson, and Peter A. Ward Chest May 1983: 44S–45S. [PDF]

Acute and Progressive Lung Injury Secondary to Toxic Oxygen Products From Leukocytes
J. C. Fantone, K. J. Johnson, G. O. Till, and Peter A. Ward Chest May 1983: 46S–48S. [PDF]

Hydrogen Peroxide Causes Permeability Edema and Hypertension in Isolated Salt-Perfused Rabbit Lungs
Robert M. Tate and John E. Repine Chest May 1983: 48S–50S. [PDF]

Importance of Oxygen Free Radicals in Asbestos-Induced Injury to Airway Epithelial Cells
Brooke T. Mossman and Joanne M. Landesman Chest May 1983: 50S–51S. [PDF]

Nitrofurantoin: Potential Direct and Indirect Mechanisms of Lung Injury
W. J. Martin, II Chest May 1983: 51S–52S. [PDF]

Prevention of Free Radical Mediated Vascular Permeability Increases in Lung Using Superoxide Dismutase
J. C. Parker, D. J. Martin, G. Rutili, J. McCord, and A. E. Taylor Chest May 1983: 52S–53S. [PDF]

Proteases and Lung Injury: A State-of-the-Art Minireview
Aaron Janoff Chest May 1983: 54S–58S. [PDF]

The Role of Tissue Repair and Leukocytes in the Pathogenesis of Emphysema
John R. Hoidal and Dennis E. Niewoehner Chest May 1983: 58S–59S. [PDF]

Role of Proteolytic and Oxidative Products of the Neutrophil in Determining the Specificity of the Pulmonary Lesion in Fibrotic and Destructive Lung Disease
J. E. Gadek, G. A. Fells, R. L. Zimmerman, B. A. Keogh, and R. G. Crystal Chest May 1983: 59S. [PDF]

Human Neutrophil Elastase within Human Alveolar Macrophages: Implications for Lung Injury
Edward J. Campbell and Mark S. Wald Chest May 1983: 59S–60S. [PDF]

Elastolytic Proteinases of the Human Macrophage
Robert A. Sandhaus, Kathleen M. McCarthy, Robert A. Musson, and Peter M. Henson Chest May 1983: 60S–62S. [PDF]

Cigarette Smoke-Elastase Interactions in the Pathogenesis of Emphysema
Dennis E. Niewoehner and John R. Hoidal Chest May 1983: 62S–63S. [PDF]

Cigarette Smoke Blocks Cross-linking of Elastin In Vitro
P. Laurent, A. Janoff, and H. M. Kagan Chest May 1983: 63S–65S. [PDF]

Smokers Do Not Have Less Functional Alpha₁-Protease Inhibitor in Their Lower Respiratory Tracts Than Nonsmokers
P. J. Stone, J. D. Calore, S. E. McGowan, J. Bernardo, G. L. Snider, and C. Franzblau Chest May 1983: 65S–66S. [PDF]

Biochemical Factors in Pulmonary Inflammatory Disease
Charles G. Cochrane, Roger G. Spragg, Susan D. Revak, and Ingrid Schraufstatter Chest May 1983: 67S–70S. [PDF]

Prostaglandins and Lung Injury
Kenneth L. Brigham, Martin Ogletree, James Snapper, James Hinson, and Richard Parker Chest May 1983: 70S–72S. [PDF]

Pulmonary Vascular Responses to Thromboxane A₂ as Unmasked by OKY-1581: A Novel Inhibitor of Thromboxane Synthesis
P. J. Kadowitz, P. A. Nandiwada, E. W. Spannhake, R. S. Rosenson, D. B. McNamara, and A. L. Hyman Chest May 1983: 72S–74S. [PDF]

Selective Blockade of Thromboxane A₂ Synthesis during Experimental E coli Bacteremia in the Goat: Effects on Hemodynamics and Lung Water
J. Harlan, R. Winn, J. Weaver, J. Hildebrandt, and L. Harker Chest May 1983: 75S–76S. [PDF]

Role of Thromboxane in the Pulmonary Response to Pulmonary Microembolization
R. R. Garcia Szabo, F. L. Minnear, R. Bizios, A. Johnson, and A. B. Malik Chest May 1983: 76S–78S. [PDF]

Platelet-Induced Pulmonary Hypertension and Edema: A Mechanism involving Acetyl Glyceryl Ether Phosphorylcholine and Thromboxane A₂
John E. Heffner, Steven A. Shoemaker, E. Michael Canham, Mahesh Patel, Ivan F. McMurtry, Helen G. Morris, and John E. Repine Chest May 1983: 78S–79S. [PDF]

Production of Cyclooxygenase Products by Alveolar Macrophages in Pulmonary Sarcoidosis
Nicholas J. Wolter, Steven L. Kunkel, Joseph P. Lynch, III, and Peter A. Ward Chest May 1983: 79S–81S. [PDF]

Quantitation and Characterization of Leukotriene Products Released following Immunologic Stimulation of Human Lung Cells in Vitro
A. G. Leitch, R. A. Lewis, E. J. Corey, and K. F. Austen Chest May 1983: 81S–82S. [PDF]

Role of Prostaglandins and Leukotrienes in Complement-Initiated Lung Vascular Injury
Marlys H. Gee, Sandra Z. Perkowski, Andrew M. Havill, and John T. Flynn Chest May 1983: 82S–85S. [PDF]

Leukotriene C₄ and D₄ Increase Pulmonary Vascular Permeability in Excised Rabbit Lungs
R. K. Albert, G. M. Greenberg, and W. Henderson Chest May 1983: 85S–86S. [PDF]

Circulating Polymorphonuclear Leukocyte Activity in Patients with the Adult Respiratory Distress Syndrome: Implications for Pulmonary Vascular Injury
G. A. Zimmerman, A. D. Renzetti, and H. R. Hill Chest May 1983: 87S–89S. [PDF]

Pneumococcal Killing in the Alveolus: Evidence for a Nonphagocytic Defense Mechanism for Early Clearance
J. D. Coonrod, S. R. Rehm, and K. Yoneda Chest May 1983: 89S–90S. [PDF]

Protection of Alpha-1 Protease Inhibitor by Plasma Antioxidants: Potential Abnormality in Chronic Obstructive Pulmonary Disease (COPD)
J. C. Taylor, L. Oey, and C. Mittman Chest May 1983: 90S–92S. [PDF]

Fibroblasts: Important Producers and Targets of Inflammatory Prostaglandins in the Lungs
S. I. Rennard, J. Moss, J. Oberpriller, B. Hom, L. Stier, T. Ozaki, and R. G. Crystal Chest May 1983: 92S–93S. [PDF]

Lipoprotein Profiles in Sheep Plasma and Lung Lymph
C. E. Cross, T. M. Forte, R. A. Gunther, G. C. Kramer, F. T. Lindgren, and R. Demling Chest May 1983: 93S–94S. [PDF]

Lung Repair and Granuloma Formation: Tubercle Bacilli Stimulated Neutrophils Release Chemotactic Factors for Monocytes
Veena B. Antony, Steven A. Sahn, Ruth N. Harada, and John E. Repine Chest May 1983: 95S–96S. [PDF]

Role of Fibronectin in Fibrotic Lung Disease: A Growth Factor for Human Lung Fibroblasts
P. Bitterman, S. Rennard, S. Adelberg, and R. G. Crystal Chest May 1983: 96S. [PDF]

The Myofibroblast in Pulmonary Fibrosis
John N. Evans, Jason Kelley, Judy Krill, Robert B. Low, and Kenneth B. Adler Chest May 1983: 97S–98S. [PDF]

Pulmonary Oxygen Toxicity: Connective Tissue Changes during Injury and Repair
David J. Riley, Janet S. Kerr, Shiu Y. Yu, Richard A. Berg, and Norman H. Edelman Chest May 1983: 98S–99S. [PDF]

Conference Summary
Thomas Stossel Chest May 1983: 100S–103S. [PDF]